USP19 Antibody

Product Discontinued

USP19 Antibody Summary

• Immunogen: Peptide with sequence RSRNPGKDDCAKE corresponding to internal region according to NP_006668.1.
• Epitope: internal region
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: USP19
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:8000
• Application Notes: WB: Preliminary experiments in human testis and heart lysates and in lysates of HEK293, A549 and HepG2 gave no specific signal but low background.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for USP19 Antibody

• Deubiquitinating enzyme 19
• EC 3.1.2.15
• EC 3.4.19.12
• KIAA0891
• Ubiquitin Carboxyl-Terminal Hydrolase 19
• ubiquitin specific peptidase 19
• ubiquitin thioesterase 19
• Ubiquitin Thiolesterase 19
• Ubiquitin-specific-processing protease 19
• USP19
• Zinc finger MYND domain-containing protein 9
• ZMYND9
• ZMYND9ubiquitin specific protease 19

Background

Ubiquitin (Ub) is a highly conserved protein found ubiquitously in eukaryotic organisms. The conjugation of ubiquitin to proteins is an important means to regulate protein activity for many cellular processes by tagging them for degradation. Removal of Ub can rescue proteins from degradation. This is accomplished by the ubiquitin-specific processing protease (UBP) family of enzymes. Ubiquitin specific processing protease 19 (USP19) is a member of this family. USP19 is a 146 kDa protein that contains two CS domains and one MYND-type zinc finger.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for USP19 Antibody (NBP1-20995)(1)

Publication using NBP1-20995

• Zhu X, Menard R, Sulea T. High incidence of ubiquitin-like domains in human ubiquitin-specific proteases. Proteins 2007-10-01 [PMID: 17597129]

Bioinformatics

• Gene Symbol: USP19
• Entrez:
  • 10869(Human)
• Uniprot:
  • NP_006668.1(Human)