UBR1 Antibody (4G7) - Azide and BSA Free

Immunocytochemistry/Immunofluorescence: UBR1 Antibody (4G7) [H00197131-M02] - Analysis of monoclonal antibody to UBR1 on HeLa cell . Antibody concentration 10 ug/ml.

ELISA: UBR1 Antibody (4G7) [H00197131-M02] - Detection limit for recombinant GST tagged UBR1 is 0.3 ng/ml as a capture antibody.

• Reactivity: Hu
• Applications: ELISA, ICC/IF
• Clone: 4G7
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Format: Azide and BSA Free

UBR1 Antibody (4G7) - Azide and BSA Free Summary

• Description: Novus Biologicals Mouse UBR1 Antibody (4G7) - Azide and BSA Free (H00197131-M02) is a monoclonal antibody validated for use in ELISA and ICC/IF. All Novus Biologicals antibodies are covered by our 100% guarantee.
• Immunogen: UBR1 (NP_777576, 2 a.a. ~ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. ADEEAGGTERMEISAELPQTPQRLASWWDQQVDFYTAFLHHLAQLVPEIYFAEMDPDLEKQEESVQMSIFTPLEWYLFGEDPDICLEKLKHSGAFQLCG
• Specificity: This product is specific for Human UBR1 monoclonal antibody (M02), clone 4G7 [Gene ID: 197131].
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: UBR1
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
• Application Notes: Mouse monoclonal antibody raised against a partial recombinant UBR1.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: In 1x PBS, pH 7.4
• Preservative: No Preservative
• Purity: IgG purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for UBR1 Antibody (4G7) - Azide and BSA Free

• E3 ubiquitin-protein ligase UBR1
• E3a ligase
• EC 6.3.2.-
• JBS
• MGC142065
• MGC142067
• N-recognin-1
• ubiquitin ligase E3 alpha-I
• ubiquitin protein ligase E3 component n-recognin 1
• ubiquitin-protein ligase E3-alpha
• Ubiquitin-protein ligase E3-alpha-1
• Ubiquitin-protein ligase E3-alpha-I

Background

The N-end rule pathway is one proteolytic pathway of the ubiquitin system. The recognition component of this pathway, encoded by this gene, binds to a destabilizing N-terminal residue of a substrate protein and participates in the formation of a substrate-linked multiubiquitin chain. This leads to the eventual degradation of the substrate protein. The protein described in this record has a RING-type zinc finger and a UBR-type zinc finger. Mutations in this gene have been associated with Johanson-Blizzard syndrome.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: UBR1
• Uniprot:
  • NP_777576(Human)