UbcH8/Ube2L6 Antibody (k1H3) [Alexa Fluor™ Plus 647]

• Reactivity: Hu
• Applications: WB, ELISA, ICC/IF, IHC
• Clone: k1H3
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor Plus 647

UbcH8/Ube2L6 Antibody (k1H3) [Alexa Fluor™ Plus 647] Summary

• Immunogen: Recombinant human UbcH8/Ube2L6 (1-152aa) purified from E. coli
• Isotype: IgG2b Kappa
• Clonality: Monoclonal
• Host: Mouse
• Gene: UBE2L6
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Immunocytochemistry/ Immunofluorescence
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein G purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for UbcH8/Ube2L6 Antibody (k1H3) [Alexa Fluor™ Plus 647]

• EC 6.3.2.19
• retinoic acid induced gene B protein
• Retinoic acid-induced gene B protein
• RIG-B
• UbcH8
• UBCH8MGC40331
• UBE2L6
• Ubiquitin carrier protein L6
• ubiquitin/ISG15-conjugating enzyme E2 L6
• ubiquitin-conjugating enzyme E2L 6
• Ubiquitin-protein ligase L6

Background

Ubiquitin-conjugating enzyme E2L6 (UBE2L6), also known as UbcH8, is a member of the E2 ubiquitin-conjugating enzyme family. The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination of a protein substrate requires the concerted action of 3 classes of enzymes: E1 ubiquitin-activating enzymes, E2 ubiquitin-conjugating enzymes, and E3 ubiquitin protein ligases. The E2 ubiquitin-conjugating enzyme is highly similar in primary structure to the enzyme encoded by UBE2L3 gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: UBE2L6