UbcH5b/UBE2D2 Antibody (OTI2C2) [mFluor Violet 610 SE]

• Reactivity: Hu, Mu, Rt
• Applications: WB, IHC
• Clone: OTI2C2
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 610 SE

UbcH5b/UBE2D2 Antibody (OTI2C2) [mFluor Violet 610 SE] Summary

• Immunogen: Full length human recombinant protein of human UBE2D2 (NP_003330) produced in E.coli.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Gene: UBE2D2
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for UbcH5b/UBE2D2 Antibody (OTI2C2) [mFluor Violet 610 SE]

• E2(17)KB2
• EC 6.3.2.19
• PUBC1
• UBC4/5
• UBC4ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC4/5)
• UBC5B
• UBCH4
• UbcH5b
• UBE2D2
• Ubiquitin carrier protein D2
• ubiquitin-conjugating enzyme E2 D2
• Ubiquitin-conjugating enzyme E2(17)KB 2
• Ubiquitin-conjugating enzyme E2-17 kDa 2
• ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)
• Ubiquitin-protein ligase D2

Background

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: UBE2D2