Species: Hu, Mu, Rt
Applications: WB, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, ELISA, IHC
Host: Mouse Monoclonal
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC
Host: Rabbit Polyclonal
Species: Hu
Applications: WB
Species: Hu
Applications: Enzyme Activity
Species: Hu
Applications: AC
Description
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme functions in the ubiquitination of the tumor-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase. Two alternatively spliced transcript variants have been found for this gene and they encode distinct isoforms.
Bioinformatics
| Product By Gene ID |
7322 |
| Alternate Names |
- E2(17)KB2
- EC 6.3.2.19
- PUBC1
- UBC4/5
- UBC4ubiquitin-conjugating enzyme E2D 2 (homologous to yeast UBC4/5)
- UBC5B
- UBCH4
- UbcH5b
- UBE2D2
- Ubiquitin carrier protein D2
- ubiquitin-conjugating enzyme E2 D2
- Ubiquitin-conjugating enzyme E2(17)KB 2
- Ubiquitin-conjugating enzyme E2-17 kDa 2
- ubiquitin-conjugating enzyme E2D 2 (UBC4/5 homolog, yeast)
- Ubiquitin-protein ligase D2
|
Research Areas for UbcH5b/UBE2D2
Find related products by research area and learn more about each of the different research areas below.
CancerHypoxia
