TRAILR1/TNFRSF10A Antibody Pair [HRP] Summary
| Description |
Solid Phase sandwich ELISA for the quantitative determination of Human TRAILR1/TNFRSF10A. |
| Specificity |
This solid phase sandwich ELISA utilizes a monoclonal antibody specific for Human TRAILR1/TNFRSF10A. |
| Standard Curve Range |
2.34-150 pg/ml (example only; lot dependent) |
| Sensitivity |
2.34 pg/ml (example only; lot dependent) |
| Assay Type |
Sandwich ELISA |
| Sample Volume |
100 ul |
| Gene |
TNFRSF10A |
Applications/Dilutions
Packaging, Storage & Formulations
| Storage |
Storage of components varies. See protocol for specific instructions. |
Kit Components
|
Components
|
- Mouse Monoclonal Capture Antibody
- Standard
|
Alternate Names for TRAILR1/TNFRSF10A Antibody Pair [HRP]
Background
TRAIL-R1 (CD261, DR4) is a type I transmembrane protein, also called TRAIL receptor 1. The ligand for this DR4 death receptor has been identified and termed TRAIL, which is a member of the TNF family. DR4, as many other receptors (Fas, TNFR1, etc.), mediates apoptosis and NF kappaB activation in many cells and tissues. Apoptosis, a programmed cell death, is a operating process in normal cellular differentiation and development of multicellular organisms. Apoptosis is induced by coupled of certain cytokines (TNF family - TNF, Fas ligand) and their death domain containing receptors (TNFR1, Fas receptor).
Limitations
This product is for research use only and is not approved for use in humans or in clinical diagnosis. Antibody Pairs are
guaranteed for 6 months from date of receipt.
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