TMC1 Antibody [mFluor Violet 610 SE]

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Product Details

Summary
Reactivity Hu, Mu, RtSpecies Glossary
Applications WB, ELISA, IHC
Clonality
Polyclonal
Host
Rabbit
Conjugate
mFluor Violet 610 SE

Order Details

TMC1 Antibody [mFluor Violet 610 SE] Summary

Immunogen
transmembrane channel-like 1. (Uniprot# Q8TDI8)
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TMC1
Purity
Immunogen affinity purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Immunohistochemistry
  • Western Blot
Application Notes
Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

Storage
Store at 4C in the dark.
Buffer
50mM Sodium Borate
Preservative
0.05% Sodium Azide
Purity
Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for TMC1 Antibody [mFluor Violet 610 SE]

  • DFNA36
  • DFNB11
  • DFNB7
  • transmembrane channel-like 1
  • transmembrane channel-like protein 1
  • Transmembrane cochlear-expressed protein 1
  • transmembrane, cochlear expressed, 1

Background

The TMC1 gene codes a 760 amino acid long, 87 kDA transmembrane channel-like protein 1 that is critical for the function of cochlear hair cells. The specific role of this gene, however, is unknown. This gene is known to interact with genes PRKAA1, MAP1LC3B, GABARAPL2, and NSMAF. Defects in the TMC1 gene cause deafness autosomal dominant type 36 and type 7. Additionally, it has been linked to nonsyndromic deafness, hearing loss, sensorineural hearing loss, megacolon, and enlarged vestibular aqueducts.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol

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Secondary Antibodies

 

Isotype Controls

Additional TMC1 Products

Array NBP3-45230MFV610

Research Areas for TMC1 Antibody (NBP3-45230MFV610)

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Calculators

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Bioinformatics

Gene Symbol TMC1