Recombinant Human Thioredoxin-2 Protein

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SDS-Page: Thioredoxin 2 Protein [NBC1-18542] - Thioredoxin2, 11 kDa (108 aa), confirmed by MALDI-TOF with a purity of 95% by SDS - PAGE

Product Details

Summary
Reactivity HuSpecies Glossary
Applications Func, PAGE
Concentration
1 mg/ml

Order Details

Recombinant Human Thioredoxin-2 Protein Summary

Description
An un-tagged recombinant protein corresponding to the amino acids 60-166 of Human Thioredoxin-2

Source: E.coli

Amino Acid Sequence: MTTFNIQDGP DFQDRVVNSE TPVVVDFHAQ WCGPCKILGP RLEKMVAKQH GKVVMAKVDI DDHTDLAIEY EVSAVPTVLA MKNGDVVDKF VGIKDEDQLE AFLKKLIG

Details of Functionality
Specific activity is >40 A650/cm/min/mg, obtained by measuring the increase of insulin precipitation in absorbance at 650 nm resulting from the reduction of insulin.
Source
E. coli
Protein/Peptide Type
Biologically Active Protein
Gene
TXN2
Purity
>95% pure by SDS-PAGE

Applications/Dilutions

Theoretical MW
11 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
Phosphate-buffered saline (pH 7.4)
Preservative
No Preservative
Concentration
1 mg/ml
Purity
>95% pure by SDS-PAGE

Alternate Names for Recombinant Human Thioredoxin-2 Protein

  • mitochondrial thioredoxin
  • MTRX
  • MT-TRX
  • thioredoxin 2
  • thioredoxin, mitochondrial
  • Thioredoxin2
  • Thioredoxin-2
  • Trx2
  • TXN2

Background

Thioredoxin(Trx) is a low molecular weight redox protein. Trx contains a redox active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. The Thioredoxin2 may play important roles in the regulation of the mitochondrial membrane potential and in protection against oxidant-induced apoptosis. Recombinant Thioredoxin2 was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 2 years from date of receipt.

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Bioinformatics

Gene Symbol TXN2
Entrez