TGR5/GPBAR1 Antibody

Immunohistochemistry-Paraffin: TGR5/GPBAR1 Antibody [NLS1933] - IHC analysis of TGR5 in formalin-fixed paraffin-embedded human kidney using NLS1933.

Product Discontinued

TGR5/GPBAR1 Antibody Summary

• Immunogen: Synthetic 16 amino acid peptide from 1st cytoplasmic domain of human TGR5.
• Epitope: 1st cytoplasmic domain of human
• Specificity: Human TGR5. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Equine (94%), Primate (100%), Monkey (94%), Rabbit (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: GPBAR1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 18 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gorilla (100%), Gibbon (100%), Marmoset (100%), Mouse (88%), Bat (88%), Bovine (88%), Hamster (88%), Rat (81%), Canine (81%), Opossum (81%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for TGR5/GPBAR1 Antibody

• BG37
• BG37hBG37
• G protein-coupled bile acid receptor 1
• GPBA
• GPBAR1
• GPCR19
• GPR131
• G-protein coupled bile acid receptor 1
• G-protein coupled bile acid receptor BG37
• G-protein coupled receptor GPCR19
• M-BAR
• M-BARhGPCR19
• membrane bile acid receptor
• Membrane-type receptor for bile acids
• MGC40597
• TGR5
• TGR5GPCR

Background

BG37/TGR5 is the first Bile Acid GPCR to be identified. BG37/TGR5 expression has been reported in a wide variety of tissues, especially placenta, spleen, and monocyte/macrophages. ESTs have been isolated from blood, breast, and skin libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: GPBAR1