TCTN1 Antibody

Images

 
Western Blot: TCTN1 Antibody [NBP1-77182] - Mouse kidney tissue lysate with TCTN1 antibody at (A) 1 and (B) 2ug/mL.
Immunocytochemistry/ Immunofluorescence: TCTN1 Antibody [NBP1-77182] - Human Kidney cells with TCTN1 antibody at 20 ug/mL.
Immunohistochemistry-Paraffin: TCTN1 Antibody [NBP1-77182] - Human kidney tissue with TCTN1 antibody at 5 ug/mL.

Product Details

Summary
Reactivity Hu, MuSpecies Glossary
Applications WB, ELISA, ICC/IF, IHC, IHC-P
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

TCTN1 Antibody Summary

Immunogen
Antibody was raised against a 15 amino acid synthetic peptide near the amino terminus of human TCTN1. The immunogen is located within amino acids 30 - 80 of TCTN1.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
TCTN1
Purity
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1:100-1:2000
  • ELISA 1:100-1:2000
  • Immunocytochemistry/Immunofluorescence 20 ug/mL
  • Immunohistochemistry 1:10-1:500
  • Immunohistochemistry-Paraffin 1:10-1:500
Control Peptide
TCTN1 Peptide (NBP1-77182PEP)

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
PBS
Preservative
0.02% Sodium Azide
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for TCTN1 Antibody

  • TECT1FLJ21127
  • tectonic 1
  • tectonic family member 1
  • tectonic-1

Background

TCTN1 is the founding member of the Tectonic protein family, a group of evolutionarily conserved secreted and transmembrane proteins that regulate the Hedgehog (Hh)-mediated patterning of the neural tube. During embryonic development, TCTN1 is expressed in regions that participate in Hh signaling, beginning in the gastrulation stages in the ventral node. Mice expressing mutant TCTN1 die between E13.5 and E16.5 and display holoprosencephaly, a defect associated with reduced Hh signaling, indicating the role of TCTN1 as an Hh activator. At later stages in development, TCTN1 is thought to also act as a repressor on the Hh pathway in the anterior and posterior neural tube.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Product General Protocols

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Video Protocols

WB Video Protocol
ICC/IF Video Protocol

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Secondary Antibodies

 

Isotype Controls

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Bioinformatics Tool for TCTN1 Antibody (NBP1-77182)

Discover related pathways, diseases and genes to TCTN1 Antibody (NBP1-77182). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
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Diseases for TCTN1 Antibody (NBP1-77182)

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Calculators

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Bioinformatics

Gene Symbol TCTN1
Uniprot