TCTN1 Products

Description

TCTN1 encodes a member of the tectonic family of secreted and transmembrane proteins. The orthologous gene in mouse is required for formation of most ventral cell types. It functions downstream of smoothened and rab23 to modulate hedgehog signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. Transcript Variant: This variant (3) uses an alternate exon combination in the central coding region and an alternate in-frame splice site in the 3' coding region, compared to variant 1, resulting in a shorter protein (isoform 3).

Bioinformatics

Entrez	79600 Human
Uniprot	NM_024549 Human NP_001076006 Human NP_001076007 Human
Product By Gene ID	79600
Alternate Names	TECT1FLJ21127 tectonic 1 tectonic family member 1 tectonic-1