TCP1 alpha Antibody (23c (CTA-123)) - BSA Free

• Reactivity: Mu, Rt, Ca, Ch, Ha
• Applications: WB, ICC/IF, IHC, IP
• Clone: 23c (CTA-123)
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Unconjugated
• Format: BSA Free
• Concentration: 1 mg/ml

TCP1 alpha Antibody (23c (CTA-123)) - BSA Free Summary

• Immunogen: C-terminal half of the full length murine TCP protein
• Specificity: Does not recognize primate, xenopus or yeast TCP-1.
• Isotype: IgG2c
• Clonality: Monoclonal
• Host: Rat
• Gene: TCP1
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:10 - 1:500
  • Immunohistochemistry 1:10 - 1:500
  • Immunoprecipitation 1:10 - 1:500
  • Western Blot 1:100 - 1:2000
• Application Notes: 23C binds protein A and is useful for native precipitation of CCT and golgi coatomer.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Protein G purified

Alternate Names for TCP1 alpha Antibody (23c (CTA-123)) - BSA Free

• CCT1T-complex protein 1 subunit alpha
• CCTa
• CCT-alpha
• D6S230E
• tailless complex polypeptide 1
• t-complex 1
• T-complex protein 1, alpha subunit
• TCP-1-alpha

Background

TCP1 alpha encodes a molecular chaperone that is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternate transcriptional splice variants of this gene, encoding different isoforms, have been characterized.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for TCP1 alpha Antibody (NBP2-50328)(1)

Publication using NBP2-50328

• Kotaki R, Kawashima M, Yamamoto Y et Al. Dasatinib exacerbates splenomegaly of mice inoculated with Epstein-Barr virus-infected lymphoblastoid cell lines Sci Rep 2020-03-09 [PMID: 32152351] (IF/IHC, Mouse)

Bioinformatics

• Gene Symbol: TCP1