TBX2 Antibody (393720) [Janelia Fluor® 525]

• Reactivity: Hu
• Applications: ICC/IF
• Clone: 393720
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Janelia Fluor 525

TBX2 Antibody (393720) [Janelia Fluor® 525] Summary

• Immunogen: E. coli-derived recombinant human TBX2
  Thr593-Arg702
  Accession # Q13207
• Specificity: Detects human TBX2 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human (rh) TBX3, rhTBX6, or rhT‑bet is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Gene: TBX2
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

Sold under license from the Howard Hughes Medical Institute, Janelia Research Campus.

Alternate Names for TBX2 Antibody (393720) [Janelia Fluor® 525]

• FLJ10169
• T-box 2
• T-box protein 2
• T-box transcription factor TBX2
• TBX2

Background

TBX2 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TBX2