TBL1 Antibody

Western Blot: TBL1 Antibody [NBP2-95262] - Western blot analysis was performed by loading 25 ug of various whole cell lysates probed with Rabbit anti TBL1X (NBP2-95262) at 1/1000 dilution. Arrow points to TBL1X (molecular weight 60 kDa).

Product Discontinued

TBL1 Antibody Summary

• Immunogen: A synthetic peptide corresponding to a sequence within amino acids 100-200 of human TBL1X (NP_005638.1)
• Specificity: Rabbit anti-TBL1X antibody recognizes Transducin Beta Like 1 X-Linked (TBL1X), also known as SMAP55 and F-box-like/WD repeat-containing protein TBL1X.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: TBL1X
• Purity: IgG purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:500 - 1:2000

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.05% Proclin 300
• Purity: IgG purified

Alternate Names for TBL1 Antibody

• EBI
• SMAP55
• TBL1transducin (beta)-like 1
• transducin (beta)-like 1X-linked
• X-linked

Background

TBL1 is encoded by this gene has sequence similarity with members of the WD40 repeat-containing protein family. The WD40 group is a large family of proteins, which appear to have a regulatory function. It is believed that the WD40 repeats mediate protein-protein interactions and members of the family are involved in signal transduction, RNA processing, gene regulation, vesicular trafficking, cytoskeletal assembly and may play a role in the control of cytotypic differentiation. This encoded protein is found as a subunit in corepressor SMRT (silencing mediator for retinoid and thyroid receptors) complex along with histone deacetylase 3 protein. This gene is located adjacent to the ocular albinism gene and it is thought to be involved in the pathogenesis of the ocular albinism with late-onset sensorineural deafness phenotype. This gene is highly similar to the Y chromosome TBL1Y gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TBL1X
• Uniprot:
  • O60907(Human)