TAPBPR Antibody (OTI4H5) [DyLight 488]

• Reactivity: Hu, Pm
• Applications: WB, ICC/IF, ICC/IF
• Clone: OTI4H5
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 488

TAPBPR Antibody (OTI4H5) [DyLight 488] Summary

• Immunogen: Full length human recombinant protein of human TAPBPR (NP_060479) produced in HEK293T cell.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: TAPBPL
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Immunofluorescence
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for TAPBPR Antibody (OTI4H5) [DyLight 488]

• FLJ10143
• TAP binding protein-like
• Tapasin Related Protein/TAPBPR
• Tapasin-like
• TAPASIN-R
• tapasin-related protein
• TAP-binding protein-like
• TAP-binding protein-related protein
• TAPBPL
• TAPBPR
• TAPBP-RTAP binding protein related
• TAPBPRtapasin-like

Background

Tapasin Related Protein encodes a transmembrane glycoprotein which mediates interaction between newly assembled major histocompatibility complex (MHC) class I molecules and the transporter associated with antigen processing (TAP), which is required for the transport of antigenic peptides across the endoplasmic reticulum membrane. This interaction is essential for optimal peptide loading on the MHC class I molecule. Up to four complexes of MHC class I and this protein may be bound to a single TAP molecule. This protein contains a C-terminal double-lysine motif (KKKAE) known to maintain membrane proteins in the endoplasmic reticulum. This gene lies within the major histocompatibility complex on chromosome 6. Alternative splicing results in three transcript variants encoding different isoforms.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: TAPBPL