SUZ12 Antibody [Alexa Fluor® 350]

• Reactivity: Hu
• Applications: WB, IP, ICC/IF
• Clonality: Polyclonal
• Host: Sheep
• Conjugate: Alexa Fluor 350

SUZ12 Antibody [Alexa Fluor® 350] Summary

• Immunogen: E. coli-derived recombinant human SUZ12
  Thr131-Asn305
  Accession # Q15022
• Specificity: Detects human SUZ12 in direct ELISAs and Western blots.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Sheep
• Purity Statement: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SUZ12 Antibody [Alexa Fluor® 350]

• ChET 9 protein
• CHET9
• CHET9polycomb protein SUZ12
• Chromatin precipitated E2F target 9 protein
• JJAZ1
• JJAZ1Joined to JAZF1 protein
• KIAA0160Suppressor of zeste 12 protein homolog
• suppressor of zeste 12 homolog (Drosophila)
• SUZ12

Background

SUZ12 (suppressor of zeste 12; also know as Joined to JazF1) is a 90-100 kDa member of the Polycomb group of transcriptional regulators. It is part of a transcription repression complex termed PRC2 (Polycomb repressive complex 2) that methylates histones in the nucleus, resulting in homeotic (pattern-inducing) gene silencing. Human SUZ12 is 739 amino acids (aa) in length. It contains one C2H2-type zinc finger region (aa 44-8471) and a C-terminal VEFS-box (aa 563-639). There is one potential splice form that shows a deletion of 51 aa over aa 129-197. Human SUZ12 shares 90% and 99% aa identity with mouse and canine SUZ12, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.