STK36 Antibody

Product Discontinued

STK36 Antibody Summary

• Immunogen: Peptide with sequence C-QSLPHSSPRPASAK corresponding to C-Terminus according to NP_056505.1.
• Epitope: C-QSLPHSSPRPASAK
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: STK36
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:16000
• Application Notes: WB: Preliminary experiments in human testis lysates gave no specific signal but low background.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for STK36 Antibody

• EC 2.7.11
• EC 2.7.11.1
• Fused homolog
• FUserine/threonine kinase 36, fused homolog
• KIAA1278DKFZp434N0223
• serine/threonine kinase 36 (fused homolog, Drosophila)
• serine/threonine kinase 36
• serine/threonine-protein kinase 36

Background

Serine/threonine protein kinase required for postnatal development, possibly by regulating the homeostasis of cerebral spinal fluid or ciliary function. Controls the activity of the transcriptional regulators GLI1, GLI2 and GLI3 by opposing the effect of SUFU and promoting their nuclear localization. GLI2 requires an additional function of STK36 to become transcriptionally active, but the enzyme does not need to possess an active kinase catalytic site for this to occur

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for STK36 Antibody (NBP1-52135)(1)

Publication using NBP1-52135

• Maloveryan A, Finta C, Osterlund T, Kogerman P. A possible role of mouse Fused (STK36) in Hedgehog signaling and Gli transcription factor regulation. J Cell Commun Signal 2007-12-01 [PMID: 18600476]

Bioinformatics

• Gene Symbol: STK36
• Entrez:
  • 27148(Human)
• Uniprot:
  • NP_056505.1(Human)