ST8 alpha-2,8-Sialyltransferase 8B/ST8SIA2 Recombinant Protein Antigen

• Reactivity: Hu
• Applications: AC

ST8 alpha-2,8-Sialyltransferase 8B/ST8SIA2 Recombinant Protein Antigen Summary

• Description: A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human ST8 alpha-2,8-Sialyltransferase 8B/ST8SIA2
  
  

  Source: E. coli

  Amino Acid Sequence: EEEIGNSGGRGTIRSAVNSLHSKSNRAEVVINGSSSPAVVDRSNESIKHNIQPASSKWRHNQTLSLRIRKQI

  Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

  This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein Antigen
• Gene: ST8SIA2
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

• Dilutions:
  • Antibody Competition 10-100 molar excess
• Application Notes: This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP3-17939.

  It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.

  For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com

• Theoretical MW: 25 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS and 1M Urea, pH 7.4.
• Preservative: No Preservative
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Alternate Names for ST8 alpha-2,8-Sialyltransferase 8B/ST8SIA2 Recombinant Protein Antigen

• alpha-2,8-sialyltransferase 8B 1
• alpha-2,8-sialyltransferase 8B
• EC 2.4.99
• EC 2.4.99.-
• HsT19690
• MGC116854
• MGC116857
• sialyltransferase 8 (alpha-2, 8-sialytransferase) B
• Sialyltransferase 8B
• Sialyltransferase X
• Sialytransferase St8Sia II
• SIAT8B
• SIAT8-B
• ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 2
• ST8SIA2
• ST8SiaII
• ST8SIA-II
• STX
• STXST8SiaII

Background

ST8SIA2 is encoded by this gene is a type II membrane protein that is thought to catalyze the transfer of sialic acid from CMP-sialic acid to N-linked oligosaccharides and glycoproteins. The encoded protein may be found in the Golgi apparatus and may be involved in the production of polysialic acid, a modulator of the adhesive properties of neural cell adhesion molecule (NCAM1). This protein is a member of glycosyltransferase family 29.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: ST8SIA2