SREC-II/SCARF2 Antibody [DyLight 594]

• Reactivity: Hu
• Applications: WB, B/N
• Clonality: Polyclonal
• Host: Goat
• Conjugate: DyLight 594

SREC-II/SCARF2 Antibody [DyLight 594] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant human SREC‑II/SCARF2
  Ala42-Gly442
  Accession # Q96GP6
• Specificity: Detects SREC‑II/SCARF2 in Western blots. In direct ELISAs and Western blots, less than 1% cross-reactivity with recombinant human SREC-I is observed.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: SCARF2
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Blockade of Receptor-ligand Interaction
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Antigen Affinity-purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for SREC-II/SCARF2 Antibody [DyLight 594]

• HUMZD58C02
• SCARF2
• scavenger receptor class F, member 2
• Scavenger receptor expressed by endothelial cells 2 protein
• SREC2NSR1
• SRECII
• SREC-II
• SREC-IIscavenger receptor class F member 2
• SRECRP-1
• SREPCR

Background

The protein encoded by the SCARF2 gene is similar to SCARF1/SREC-I, a scavenger receptor protein that mediates the bindingand degradation of acetylated low density lipoprotein (Ac-LDL). This protein has only little activity of internalizingmodified low density lipoproteins (LDL), but it can interact with SCARF1 through its extracellular domain. Theassociation of this protein with SCARF1 is suppressed by the presence of scavenger ligands. Alternatively splicedtranscript variants encoding distinct isoforms have been reported. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SCARF2