SPO11 Antibody [mFluor Violet 610 SE]

Product Discontinued

SPO11 Antibody [mFluor Violet 610 SE] Summary

• Immunogen: SPO11 meiotic protein covalently bound to DSB homolog. (Uniprot# Q9Y5K1)
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: SPO11
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for SPO11 Antibody [mFluor Violet 610 SE]

• Cancer/testis antigen 35
• CT35MGC39953
• meiotic recombination protein SPO11
• SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
• SPO11 meiotic protein covalently bound to DSB-like (S. cerevisiae)
• SPO11, meiotic protein covalently bound to DSB (S. cerevisiae)-like

Background

Meiotic recombination and chromosome segregation require the formation of double-strand breaks (DSBs) in paired chromosome homologs. During meiosis in yeast, a meiotic recombination protein is covalently-linked to the 5' end of DSBs and is essential for the formation of DSBs. The protein encoded by this gene is similar in sequence and conserved features to the yeast meiotic recombination protein. The encoded protein belongs to the TOP6A protein family. Several transcript variants encoding different isoforms have been found for this gene, but the full-length nature of only two of them have been described.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SPO11