SIRT7 Antibody


Western Blot: SIRT7 Antibody [NB110-81762] - SIRT7 Immunoprecipitated from human liver lysates with NB110-81762. A). NB110-81746 B). NB110-81744
Immunocytochemistry/ Immunofluorescence: SIRT7 Antibody [NB110-81762] - SIRT7 antibody was tested in U2OS cells with DyLight 488 (green). Nuclei and alpha-tubulin were counterstained with DAPI (blue) and Dylight 550 more

Product Details

Reactivity Hu, Mu, RtSpecies Glossary
Applications ICC/IF, IP
1 mg/ml

Order Details

Available Conjugates
Catalog# & Conjugate Size Price

SIRT7 Antibody Summary

Synthetic peptide made to an internal portion of human SIRT7 (within residues 50-150). [Swiss-Prot# Q9NRC8]
Cytoplasm. Note=Located under the nuclear membrane.
Immunogen affinity purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Packaging, Storage & Formulations

Store at 4C. Do not freeze.
Tris-citrate/phosphate, pH 7-8
0.1% Sodium Azide
1 mg/ml
Immunogen affinity purified


Application Notes
This SIRT7 antibody is useful for Immunocytochemistry/Immunofluorescence and Immunoprecipitation. For Western blot, catalog numbers NB110-81744 or NB110-81746 are suggested. In ICC/IF nuclear staining was observed.

The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Theoretical MW
42 kDa

Reactivity Notes

Human, mouse and rat

Alternate Names for SIRT7 Antibody

  • EC 3.5.1.-
  • MGC126840
  • MGC126842
  • silent mating type information regulation 2, S.cerevisiae, homolog 7
  • SIR2L7NAD-dependent deacetylase sirtuin-7
  • SIR2-like protein 7
  • sir2-related protein type 7
  • sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae)
  • sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 7
  • sirtuin 7
  • sirtuin type 7


Sirtuins (SIRT) are highly conserved NAD-dependent deacetylases that deacetylate histone/non-histone proteins which regulates numerous cellular processes including aging, DNA repair, cell cycle, metabolism, and survival under stress conditions. NAD-dependent protein deacetylase sirtuin-7 (SIRT7 or SIR2L7) is one of the SIRTs whose function is least understood and it may be found at peri-nuclear region of cytoplasm; associated with chromatin, rDNA promoter, transcribed regionas or nucleolar organizer regions during mitosis. SIRT7's lacks the conserved amino acids within catalytic domain associated with deacetylase actions, however, with its weak deacetylase activity, it can deacetylate tumor suppressor p53 leading to enhanced cell survival. SIRT7 complexes with ELK4 to deacetylate H3K18 at the promoters of NME1, COPS2 genes and deacetylate histone H3K18 acetylation at promoters of RPS7, RPS14, RPS20, which function as tumor suppressor genes in hematopoietic malignancy. SIRT7 connects chromatin remodeling complexes with the RNA Pol I machinery required for rDNA driving ribosome biogenesis in dividing cells. It is overexpressed in human thyroid carcinoma cell lines and tissues, but not in adenomas.


This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

Species: Ce
Applications: WB, IHC, IHC-P, IP
Species: Hu, Mu, Rt, Pm
Applications: WB, ELISA, Flow, ICC/IF, IHC, IHC-P
Species: Hu, Mu, Rt
Applications: WB, ICC/IF, IHC, IHC-Fr, IHC-P, IP
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P
Species: Hu, Mu, Rt
Applications: WB
Species: Hu, Rt
Applications: WB, IHC, IHC-P, PEP-ELISA
Species: Hu
Applications: WB, ELISA, PA
Species: Hu, Mu, Rt, Ce, Dr, Ma, Ye
Applications: WB, ChIP, DB, ELISA, ICC/IF
Species: Hu, Bv, Ca, Pm
Applications: WB, IHC, IHC-P
Species: Hu, Mu
Applications: WB, ICC/IF, IHC, IHC-P, IP
Species: Hu, Mu
Applications: WB, IP
Species: Hu
Applications: WB, ICC/IF, IHC, IHC-P, IP, PLA
Species: Hu
Applications: WB, ELISA, ICC/IF, IHC, IHC-P, S-ELISA
Applications: WB
Species: Hu
Species: Hu
Applications: WB, ELISA, PA
Species: Hu
Applications: WB, ELISA, PA
Species: Hu, Mu, Rt
Applications: ICC/IF, IP

Publications for SIRT7 Antibody (NB110-81762) (0)

There are no publications for SIRT7 Antibody (NB110-81762).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for SIRT7 Antibody (NB110-81762) (0)

There are no reviews for SIRT7 Antibody (NB110-81762). By submitting a review earn points towards our Rewards Program.
  • 250 points for product review
  • 500 additional points for an image with your product review
  • Double points (500) if you are the first to review this product
  • Double points (1000) if you are the first to review this product with an image

Product General Protocols

View specific protocols for SIRT7 Antibody (NB110-81762): Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

ICC/IF Video Protocol

FAQs for SIRT7 Antibody (NB110-81762) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Positive Control Lysate(s)

Secondary Antibodies


Isotype Controls

Other Available Formats

DyLight 405 Labeled NB110-81762V
FITC Labeled NB110-81762F

Additional SIRT7 Antibody Products

Related Products by Gene

Bioinformatics Tool for SIRT7 Antibody (NB110-81762)

Discover related pathways, diseases and genes to SIRT7 Antibody (NB110-81762). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for SIRT7 Antibody (NB110-81762)

Discover more about diseases related to SIRT7 Antibody (NB110-81762).

Pathways for SIRT7 Antibody (NB110-81762)

View related products by pathway.

PTMs for SIRT7 Antibody (NB110-81762)

Learn more about PTMs related to SIRT7 Antibody (NB110-81762).

Research Areas for SIRT7 Antibody (NB110-81762)

Find related products by research area.

Blogs on SIRT7

There are no specific blogs for SIRT7, but you can read our latest blog posts.

Contact Information

Product PDFs


Gene Symbol SIRT7

Customer Resources

Novus Review - Submit your review and earn rewards points which can be used for merchandise & discounts.
Risk Free Testing - Test on a species/application not listed above to receive a full credit towards a future purchase.

Novus' Quality Guarantee - Novus guarantees that every product we sell will work in the application and species listed on our website and datasheets.

Submit your question on NB110-81762 below.
During business hours, we will respond to your email within 24 hours. For any questions submitted on the weekend, a response will be received on Monday.
For immediate assistance during business hours M- F (excluding major holidays), please contact us.
Ask a Scientist - We have a lab full of white coats just waiting for your scientific questions and concerns.

Customers Who Bought This Also Bought