SIRT7 Antibody

Western Blot: SIRT7 Antibody [H00051547-B01P] - Analysis of SIRT7 expression in HeLa.

Immunocytochemistry/Immunofluorescence: SIRT7 Antibody [H00051547-B01P] - Analysis of purified antibody to SIRT7 on HeLa cell. (antibody concentration 10 ug/ml)

Western Blot: SIRT7 Antibody [H00051547-B01P] - Analysis of SIRT7 expression in transfected 293T cell line by SIRT7 polyclonal antibody. Lane 1: SIRT7 transfected lysate(44 KDa). Lane 2: Non-transfected lysate.

Product Discontinued

SIRT7 Antibody Summary

• Immunogen: SIRT7 (NP_057622.1, 1 a.a. - 400 a.a.) full-length human protein. MAAGGLSRSERKAAERVRRLREEQQRERLRQVSRILRKAAAERSAEEGRLLAESADLVTELQGRSRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAKYLVVYTGAGISTAASIPDYRGPNGVWTLLQKGRSVSAADLSEAEPTLTHMSITRLHEQKLVQHVVSQNCDGLHLRSGLPRTAISELHGNMYIEVCTSCVPNREYVRVFDVTERTALHRHQTGRTCHKCGTQLRDTIVHFGERGTLGQPLNWEAATEAASRADTILCLGSSLKVLKKYPRLWCMTKPPSRRPKLYIVNLQWTPKDDWAALKLHGKCDDVMRLLMAELGLEIPAYSRWQDPIFSLATPLRAGEEGSHSRKSLCRSREEAPPGDRGAPLSSAPILGGWFGRGCTKRTKRKKVT
• Specificity: SIRT7 - sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae),
• Isotype: IgG
• Clonality: Polyclonal
• Host: Mouse
• Gene: SIRT7
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence
  • Western Blot 1:500
• Application Notes: Antibody reactive against Recombinant Protein with GST tag on ELISA and Western Blot and also on transfected lysate in western blot. GST tag alone is used as a negative control. Has also been used for immunofluorescence.

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4)
• Preservative: No Preservative
• Purity: Protein A purified

Notes

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for SIRT7 Antibody

• EC 3.5.1.-
• MGC126840
• MGC126842
• silent mating type information regulation 2, S.cerevisiae, homolog 7
• SIR2L7
• SIR2L7NAD-dependent deacetylase sirtuin-7
• SIR2-like protein 7
• sir2-related protein type 7
• sirtuin (silent mating type information regulation 2 homolog) 7 (S. cerevisiae)
• sirtuin (silent mating type information regulation 2, S.cerevisiae, homolog) 7
• Sirtuin 7
• sirtuin type 7

Background

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class IV of the sirtuin family. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SIRT7
• Entrez:
  • 51547(Human)
• Uniprot:
  • NP_057622.1(Human)