Recombinant Human SGTA Protein

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SDS-Page: SGTA Protein [NBP1-44491] - SGTA, 35.1 kDa (321aa), confirmed by MALDI-TOF with a purity of 95% by SDS - PAGE

Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
1 mg/ml

Order Details

Recombinant Human SGTA Protein Summary

Description
A recombinant protein with a C-Terminal His-tag and corresponding to the amino acids 1-313 of Human SGTA

Source: E.coli

Amino Acid Sequence: MDNKKRLAYA IIQFLHDQLR HGGLSSDAQE SLEVAIQCLE TAFGVTVEDS DLALPQTLPE IFEAAATGKE MPQDLRSPAR TPPSEEDSAE AERLKTEGNE QMKVENFEAA VHFYGKAIEL NPANAVYFCN RAAAYSKLGN YAGAVQDCER AICIDPAYSK AYGRMGLALS SLNKHVEAVA YYKKALELDP DNETYKSNLK IAELKLREAP SPTGGVGSFD IAGLLNNPGF MSMASNLMNN PQIQQLMSGM ISGGNNPLGT PGTSPSQNDL ASLIQAGQQF AQQMQQQNPE LIEQLRSQIR SRTPSASNDD QQELEHHHHH H

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
SGTA
Purity
>95% pure by SDS-PAGE

Applications/Dilutions

Theoretical MW
35.1 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Tris-HCl buffer(pH 8.0) containing 10% glycerol, 1mM DTT
Preservative
No Preservative
Concentration
1 mg/ml
Purity
>95% pure by SDS-PAGE

Alternate Names for Recombinant Human SGTA Protein

  • alphaSGT
  • Alpha-SGT
  • protein containing three tetratricopeptide repeats
  • SGT1
  • SGThSGT
  • small glutamine-rich tetratricopeptide repeat (TPR)-containing
  • small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
  • small glutamine-rich tetratricopeptide repeat-containing protein alpha
  • UBP
  • Vpu-binding protein

Background

SGTA, also known as SGT or hSGT, is a ubiquitously expressed protein that contains three TPR protein-protein interaction repeats. This protien is believed to function as a component of the androgen receptor (AR)-chaperone-cochaperone complex, acting as a cochaperone involved in androgen signaling. In addition, SGTA functions as a cochaperone that binds directly to HSC70 and HSP70 and regulates their ATPase activity. On the basis of its role in apoptosis and androgen signaling, SGTA is a potential candidate for PCOS (polycystic ovary syndrome), a disorder characterized by androgen excess, obesity and menstrual disturbances. Recombinant SGTA protein, fused to His-tag at C-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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FAQs for SGTA Protein (NBP1-44491). (Showing 1 - 1 of 1 FAQ).

  1. We purchased this protein from you guys and I need its sequence.
    • NBP1-44491: full length protein, aa 1-313, with his-tag.

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Bioinformatics

Gene Symbol SGTA