SFRS18 Recombinant Protein Antigen

• Reactivity: Hu
• Applications: AC

SFRS18 Recombinant Protein Antigen Summary

• Description: A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human SFRS18
  
  

  Source: E. coli

  Amino Acid Sequence: DTDDEELRHRIRQKQEAFWRKEKEQQLLHDKQMEEEKQQTERVTKEMNEFIHKEQNSLSLLEAREADGDVVNEKKRTPNETT

  Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

  This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein Antigen
• Gene: PNISR
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

• Dilutions:
  • Antibody Competition 10-100 molar excess
• Application Notes: This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP3-17435.

  It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.

  For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com

• Theoretical MW: 28 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS and 1M Urea, pH 7.4.
• Preservative: No Preservative
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Alternate Names for SFRS18 Recombinant Protein Antigen

• bA98I9.2
• C6orf111
• chromosome 6 open reading frame 111
• DKFZp564B0769
• FLJ14752
• FLJ14992
• FLJ90147
• HSPC306
• MGC104269
• RP11-98I9.2
• Serine/arginine-rich-splicing regulatory protein 130
• serine-arginine-rich-splicing regulatory protein 130
• Splicing factor, arginine/serine-rich 130
• splicing factor, arginine/serine-rich 18
• SR rich protein
• SR-related protein
• SR-rich protein
• SRRP130
• SRrp130FLJ14853

Background

SFRS18/SRrp130 (splicing factor arginine/serine-rich 18) is a putative alternative splicing factor. It was identified as a factor that interacts with pinin (Pnn/DRS/memA), a cell-adhesion and nuclear protein of corneal epithelial cells. SFRS18/SRrp130 bears multiple arginine/serine-rich repeats found among the SR-related family of pre-mRNA processing factors. SFRS18/SRrp130 and pinin co-localize and are distributed as nuclear specks that correspond to the pre-splicing machinery.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: PNISR