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sFRP-3/FRZB Antibody (4F7)

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Western Blot: sFRP-3/FRZB Antibody (4F7) [H00002487-M01] - Analysis of FRZB expression in transfected 293T cell line by FRZB monoclonal antibody (M01), clone 4F7.Lane 1: FRZB transfected lysate(36.3 KDa).Lane 2: Non-transfected lysate.
Western Blot: sFRP-3/FRZB Antibody (4F7) [H00002487-M01] - Analysis of FRZB expression in transfected 293T cell line by FRZB monoclonal antibody (M01), clone 4F7.Lane 1: FRZB transfected lysate(36.3 KDa).Lane 2: ...read more

Product Details

Summary
Reactivity HuSpecies Glossary
Applications WB, ELISA
Clone
4F7
Clonality
Monoclonal
Host
Mouse
Conjugate
Unconjugated

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sFRP-3/FRZB Antibody (4F7) Summary

Immunogen
FRZB (NP_001454, 102 a.a. ~ 190 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. HEPIKPCKSVCERARQGCEPILIKYRHSWPENLACEELPVYDRGVCISPEAIVTADGADFPMDSSNGNCRGASSERCKCKPIRATQKTY*
Specificity
FRZB (4F7)
Isotype
IgG2a Kappa
Clonality
Monoclonal
Host
Mouse
Gene
FRZB
Purity
IgG purified
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Applications/Dilutions

Dilutions
  • ELISA
  • Western Blot 1:500
Application Notes
Antibody reactivity against Recombinant Protein with GST tag on ELISA and WB. GST tag alone is used as a negative control.

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
In 1x PBS, pH 7.4
Preservative
No Preservative
Purity
IgG purified

Notes

Quality control test: Antibody Reactive Against Recombinant Protein.

This product is produced by and distributed for Abnova, a company based in Taiwan.

Alternate Names for sFRP-3/FRZB Antibody (4F7)

  • FIZ
  • FREOS1
  • Frezzled
  • Fritz
  • Frizzled-related protein 1
  • frizzled-related protein
  • FRP
  • FRP-3
  • FRZB
  • Frzb1
  • FRZB-1
  • FRZB1sFRP-3
  • FRZB-PEN
  • FZRB
  • hFIZ
  • secreted frizzled-related protein 3
  • sFRP3
  • sFRP-3
  • SFRP3frezzled
  • SRFP3frizzled homolog-related

Background

Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interactionwith Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP3/FRZB appearsto be involved in limb skeletogenesis. Antagonist of Wnt8 signaling. Regulates chondrocyte maturation and long bonedevelopment

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol FRZB
Entrez
OMIM
Uniprot