SF3A2 Antibody (4G8)

Product Discontinued

SF3A2 Antibody (4G8) Summary

• Immunogen: C-terminal for SF3A2 protein was used as the immunogen for this antibody.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: SF3A2
• Purity: Protein G purified

Applications/Dilutions

• Dilutions:
  • Immunofluorescence
  • Immunoprecipitation
  • Western Blot

Packaging, Storage & Formulations

• Storage: Lyophilized antibody can be kept at 4C for up to 3 months and should be kept at -20C for long-term storage. To avoid freeze-thaw cycles, reconstituted antibody should be aliquoted before freezing for short-term storage (-20C) or for long-term storage (-80C). For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.
• Buffer: PBS
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein G purified
• Reconstitution Instructions: Reconstitute with 0.1 ml water.

Alternate Names for SF3A2 Antibody (4G8)

• pre-mRNA splicing factor SF3A, subunit 2
• PRP11
• PRPF11
• SAP 62
• SAP62Prp11
• SF3a66splicing factor 3a, subunit 2, 66kD
• spliceosome associated protein 62
• Spliceosome-associated protein 62
• splicing factor 3A subunit 2
• splicing factor 3a, subunit 2, 66kDa

Background

SF3A2 encodes subunit 2 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 2 interacts with subunit 1 through its amino-terminus while the single zinc finger domain of subunit 2 plays a role in its binding to the 15S U2 snRNP. Subunit 2 may also function independently of its RNA splicing function as a microtubule-binding protein.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SF3A2
• Uniprot:
  • Q15428(Human)