SERPINB13 Antibody (OTI2B6)

Western Blot: SERPINB13 Antibody (2B6) [NBP2-01312] - HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY SERPINB13 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 ug per lane) were separated by SDS-PAGE and immunoblotted with anti-SERPINB13.

Immunohistochemistry: SERPINB13 Antibody (OTI2B6) [NBP2-01312] - Cytoplasmic staining was detected for Serpin B13 protein in the malignant epithelium of breast cancer. The majority of 'pure' HER2+ (HER2+/ER-/PR-) tumours showed loss of SERPIN B13 staining. Image collected and cropped by CiteAb from the following publication (//www.nature.com/articles/s41419-018-0364-9), licensed under a CC-BY license.

Immunohistochemistry-Paraffin: SERPINB13 Antibody (2B6) [NBP2-01312] - Staining of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-SERPINB13 mouse monoclonal antibody.

Immunohistochemistry-Paraffin: SERPINB13 Antibody (2B6) [NBP2-01312] - Staining of paraffin-embedded Carcinoma of Human bladder tissue using anti-SERPINB13 mouse monoclonal antibody.

Immunohistochemistry-Paraffin: SERPINB13 Antibody (2B6) [NBP2-01312] - Staining of paraffin-embedded Human Kidney tissue using anti-SERPINB13 mouse monoclonal antibody.

Immunohistochemistry-Paraffin: SERPINB13 Antibody (2B6) [NBP2-01312] Staining of paraffin-embedded Human liver tissue using anti-SERPINB13 mouse monoclonal antibody.

Immunohistochemistry: SERPINB13 Antibody (OTI2B6) [NBP2-01312] - Cytoplasmic staining was detected for (a) MTSS1, (b) SCAMP1 & (c) Serpin B13 protein in the malignant epithelium of breast cancer. Alternatively, the majority of ‘pure’ HER2+ (HER2+/ER−/PR−) tumours showed loss or in (d) MTSS1, (e) SCAMP1 & (f) SERPIN B13 staining. g Distribution of MTSS1, SCAMP1 & SERPIN B13 in the ‘pure’ HER2 patient class versus other tumour classes Image collected & cropped by CiteAb from the following publication (//www.nature.com/articles/s41419-018-0364-9), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

Immunohistochemistry: SERPINB13 Antibody (OTI2B6) [NBP2-01312] - Cytoplasmic staining was detected for (a) MTSS1, (b) SCAMP1 & (c) Serpin B13 protein in the malignant epithelium of breast cancer. Alternatively, the majority of ‘pure’ HER2+ (HER2+/ER−/PR−) tumours showed loss or in (d) MTSS1, (e) SCAMP1 & (f) SERPIN B13 staining. g Distribution of MTSS1, SCAMP1 & SERPIN B13 in the ‘pure’ HER2 patient class versus other tumour classes Image collected & cropped by CiteAb from the following publication (//www.nature.com/articles/s41419-018-0364-9), licensed under a CC-BY license. Not internally tested by Novus Biologicals.

• Reactivity: Hu
• Applications: WB, IHC
• Clone: OTI2B6
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Unconjugated
• Concentration: 1 mg/ml

SERPINB13 Antibody (OTI2B6) Summary

• Immunogen: Full length human recombinant protein of human SERPINB13(NP_036529) produced in HEK293T cell.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: SERPINB13
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry 1:150
  • Immunohistochemistry-Paraffin 1:150
  • Western Blot 1:2000
• Theoretical MW: 44.1 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.3), 1.0% BSA and 50% Glycerol
• Preservative: 0.02% Sodium Azide
• Concentration: 1 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for SERPINB13 Antibody (OTI2B6)

• HaCaT UV-repressible serpin
• headpin
• HSHUR7SEQ
• HUR7
• HURPIN
• MGC126870
• Peptidase inhibitor 13
• PI-13
• PI13hurpin
• protease inhibitor 13 (hurpin, headpin)
• Proteinase inhibitor 13
• serine (or cysteine) proteinase inhibitor, clade B (ovalbumin), member 13
• serpin B13
• serpin peptidase inhibitor, clade B (ovalbumin), member 13
• UV-B repressed sequence, HUR 7

Background

SERPINB13 may play a role in the proliferation or differentiation of keratinocytes

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for SERPINB13 Antibody (NBP2-01312)(1)

Publication using NBP2-01312

• Vadakekolathu J, Al-Juboori SIK, Johnson C et al. MTSS1 and SCAMP1 cooperate to prevent invasion in breast cancer. Cell Death Dis. 2018-03-01 [PMID: 29497041] (IF/IHC, Human)

Bioinformatics

• Gene Symbol: SERPINB13
• Entrez:
  • 5275(Human)