Serpin I2 Antibody (7H7)

Product Discontinued

Serpin I2 Antibody (7H7) Summary

• Immunogen: The immunogen for this antibody is SERPINI2.
• Isotype: IgM
• Clonality: Monoclonal
• Host: Mouse
• Gene: SERPINI2
• Purity: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:1000
• Theoretical MW: 46 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS and 2% Sucrose
• Preservative: 0.09% Sodium Azide
• Purity: Protein A or G purified

Notes

The addition of 50% glycerol is optional for those storing this antibody at -20C and not aliquoting smaller units. However, please note that glycerol may interrupt some downstream antibody applications and should be added with caution.

Alternate Names for Serpin I2 Antibody (7H7)

• MEPI
• MEPIpancpin
• Myoepithelium-derived serine protease inhibitor
• Pancipin
• Pancpin
• Pancreas-specific protein TSA2004
• Peptidase inhibitor 14
• PI14
• PI-14
• PI14clade I (neuroserpin), member 2
• protease inhibitor 14
• serine (or cysteine) proteinase inhibitor, clade I (pancpin), member 2
• Serpin I2
• serpin peptidase inhibitor, clade I (pancpin), member 2
• SERPIN12

Background

The protein encoded by this gene is a member of the serine protease inhibitor (serpin) superfamily made up of proteins which play central roles in the regulation of a wide variety of physiological processes, including coagulation, fibrinolysis, development, malignancy and inflammation. The gene product may have a role in a growth-control, possibly growth-suppressing pathway and, when impaired, may be involved in pancreatic carcinogenesis. The protein is a member of the plasminogen activator inhibitor-1 family, a subset of the serpin superfamily whose members act as tissue-specific tPA inhibitors. Two alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SERPINI2
• Uniprot:
  • NP_006208(Human)