Serpin I2 Products

Description

SERPINI2 is encoded by this gene is a member of the serine protease inhibitor (serpin) superfamily made up of proteins which play central roles in the regulation of a wide variety of physiological processes, including coagulation, fibrinolysis, development, malignancy and inflammation. The gene product may have a role in a growth-control, possibly growth-suppressing pathway and, when impaired, may be involved in pancreatic carcinogenesis. The protein is a member of the plasminogen activator inhibitor-1 family, a subset of the serpin superfamily whose members act as tissue-specific tPA inhibitors. Two alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene.

Bioinformatics

Entrez	171149 Rat 5276 Human 67931 Mouse
Uniprot	NP_006208 Human NP_006208.1 Human O75830 Human O75830.1 Human
Product By Gene ID	5276
Alternate Names	MEPIpancpin Myoepithelium-derived serine protease inhibitor Pancpin Pancreas-specific protein TSA2004 Peptidase inhibitor 14 PI-14 PI14clade I (neuroserpin), member 2 protease inhibitor 14 serine (or cysteine) proteinase inhibitor, clade I (pancpin), member 2 serpin I2 serpin peptidase inhibitor, clade I (pancpin), member 2 SERPIN12