Serpin I2 Antibody (02)

Immunohistochemistry-Paraffin: Serpin I2 Antibody (02) [NBP3-06556] - Staining of human SERPINI2 in human pancreas with mouse monoclonal antibody (1:1000).

Product Discontinued

Serpin I2 Antibody (02) Summary

• Description: This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.
• Immunogen: This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human Serpin I2 (NP_006208.1; Met1-Leu405).
• Isotype: IgG
• Clonality: Monoclonal
• Host: Mouse
• Gene: SERPINI2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 1:500-1:2000

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 0.2 um filtered solution in PBS
• Preservative: No Preservative
• Purity: Protein A purified

Alternate Names for Serpin I2 Antibody (02)

• MEPI
• MEPIpancpin
• Myoepithelium-derived serine protease inhibitor
• Pancipin
• Pancpin
• Pancreas-specific protein TSA2004
• Peptidase inhibitor 14
• PI14
• PI-14
• PI14clade I (neuroserpin), member 2
• protease inhibitor 14
• serine (or cysteine) proteinase inhibitor, clade I (pancpin), member 2
• Serpin I2
• serpin peptidase inhibitor, clade I (pancpin), member 2
• SERPIN12

Background

SERPINI2 is encoded by this gene is a member of the serine protease inhibitor (serpin) superfamily made up of proteins which play central roles in the regulation of a wide variety of physiological processes, including coagulation, fibrinolysis, development, malignancy and inflammation. The gene product may have a role in a growth-control, possibly growth-suppressing pathway and, when impaired, may be involved in pancreatic carcinogenesis. The protein is a member of the plasminogen activator inhibitor-1 family, a subset of the serpin superfamily whose members act as tissue-specific tPA inhibitors. Two alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SERPINI2