Serpin I2 Antibody (018) [Alexa Fluor™ Plus 594]

• Reactivity: Hu
• Applications: ELISA, Flow
• Clone: 018
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Alexa Fluor Plus 594

Serpin I2 Antibody (018) [Alexa Fluor™ Plus 594] Summary

• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: This antibody was obtained from a rabbit immunized with purified, recombinant Human Serpin I2 (Accession#: NP_006208.1; Met 1-Leu 405).
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: SERPINI2
• Purity: Protein A purified

Applications/Dilutions

• Dilutions:
  • ELISA
  • Flow Cytometry
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A purified

Notes

This product is provided under an intellectual property license from Life Technologies Corporation. The transfer of this product is conditioned on the buyer using the purchased product solely in research conducted by the buyer, excluding contract research or any fee for service research, and the buyer must not (1) use this product or its components for (a) diagnostic, therapeutic or prophylactic purposes; (b) testing, analysis or screening services, or information in return for compensation on a per-test basis; or (c) manufacturing or quality assurance or quality control, and/or (2) sell or transfer this product or its components for resale, whether or not resold for use in research. For information on purchasing a license to this product for purposes other than as described above, contact Life Technologies Corporation, 5781 Van Allen Way, Carlsbad, CA 92008 USA or outlicensing@thermofisher.com. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for Serpin I2 Antibody (018) [Alexa Fluor™ Plus 594]

• MEPI
• MEPIpancpin
• Myoepithelium-derived serine protease inhibitor
• Pancipin
• Pancpin
• Pancreas-specific protein TSA2004
• Peptidase inhibitor 14
• PI14
• PI-14
• PI14clade I (neuroserpin), member 2
• protease inhibitor 14
• serine (or cysteine) proteinase inhibitor, clade I (pancpin), member 2
• Serpin I2
• serpin peptidase inhibitor, clade I (pancpin), member 2
• SERPIN12

Background

SERPINI2 is encoded by this gene is a member of the serine protease inhibitor (serpin) superfamily made up of proteins which play central roles in the regulation of a wide variety of physiological processes, including coagulation, fibrinolysis, development, malignancy and inflammation. The gene product may have a role in a growth-control, possibly growth-suppressing pathway and, when impaired, may be involved in pancreatic carcinogenesis. The protein is a member of the plasminogen activator inhibitor-1 family, a subset of the serpin superfamily whose members act as tissue-specific tPA inhibitors. Two alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SERPINI2