Serpin I1/Neuroserpin Antibody

Images

 
Western Blot: Serpin I1/Neuroserpin Antibody [NBP1-31037] - Mouse tissue extract (50 ug) was separated by 10% SDS-PAGE, and the membrane was blotted with Neuroserpin antibody [C3], C-term diluted at 1:500.
Western Blot: Serpin I1/Neuroserpin Antibody [NBP1-31037] - Sample(30 ug of whole cell lysate)A:A431 B:HeLa S3 C:Hep G2 10% SDS PAGE, antibody diluted at 1:1500.

Product Details

Summary
Reactivity Hu, Mu, Rt, MkSpecies Glossary
Applications WB
Clonality
Polyclonal
Host
Rabbit
Conjugate
Unconjugated
Concentration
1 mg/ml

Order Details

Serpin I1/Neuroserpin Antibody Summary

Immunogen
Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human Neuroserpin. The exact sequence is proprietary.
Localization
Secreted
Predicted Species
Rat (100%), Monkey (100%). Backed by our 100% Guarantee.
Isotype
IgG
Clonality
Polyclonal
Host
Rabbit
Gene
SERPINI1
Purity
Immunogen affinity purified
Innovator's Reward
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Applications/Dilutions

Dilutions
  • Western Blot 1:500-1:3000
Theoretical MW
46 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Reactivity Notes

Rhesus Monkey (100%).

Packaging, Storage & Formulations

Storage
Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Buffer
PBS (pH 7.0) and 10% Glycerol
Preservative
0.01% Thimerosal
Concentration
1 mg/ml
Purity
Immunogen affinity purified

Alternate Names for Serpin I1/Neuroserpin Antibody

  • DKFZp781N13156
  • Neuroserpin
  • Peptidase inhibitor 12
  • PI12
  • PI-12
  • PI12Serpin I1
  • serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 1
  • Serpin I1
  • serpin peptidase inhibitor, clade I (neuroserpin), member 1

Background

This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq]

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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Bioinformatics

Gene Symbol SERPINI1
Entrez