SEC6 Antibody (23GB5345)

• Reactivity: Hu, Mu, Rt
• Applications: WB, Flow
• Clone: 23GB5345
• Clonality: Monoclonal
• Host: Rabbit
• Conjugate: Unconjugated

SEC6 Antibody (23GB5345) Summary

• Immunogen: A synthesized peptide derived from human SEC6 (Uniprot: O60645)
• Isotype: IgG
• Clonality: Monoclonal
• Host: Rabbit
• Gene: EXOC3
• Purity: Affinity purified

Applications/Dilutions

• Dilutions:
  • Flow Cytometry
  • Western Blot

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7.4), 50% glycerol
• Preservative: 0.02% Sodium Azide
• Purity: Affinity purified

Alternate Names for SEC6 Antibody (23GB5345)

• exocyst complex component 3
• Exocyst complex component Sec6
• Sec 6 homolog
• SEC6
• SEC6L1
• SEC6-like 1 (S. cerevisiae)
• SEC6-like 1
• Sec6p

Background

SEC6 is encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: EXOC3