SDNSF/MCFD2 Antibody (300812) [Alexa Fluor® 750]

• Reactivity: Mu
• Applications: IHC
• Clone: 300812
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor 750

SDNSF/MCFD2 Antibody (300812) [Alexa Fluor® 750] Summary

• Immunogen: Mouse myeloma cell line NS0-derived recombinant mouse SDNSF/MCFD2
  His27-Gln145 (predicted)
  Accession # Q8K5B2
• Specificity: Detects mouse SDNSF/MCFD2 in direct ELISAs. In direct ELISAs, no cross-reactivity with recombinant human SDNSF is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for SDNSF/MCFD2 Antibody (300812) [Alexa Fluor® 750]

• DKFZp686G21263
• F5F8D2
• LMAN1IP
• MCFD2
• multiple coagulation factor deficiency 2
• multiple coagulation factor deficiency protein 2
• neural stem cell derived neuronal survival protein
• Neural stem cell-derived neuronal survival protein
• SDNSF
• SDNSFF5F8D

Background

SDNSF, also known as MCFD2 (multiple coagulation factor deficiency 2), is a secreted molecule from adult hippocampal neural stem/progenitor cells (ANSC) that functions as an autocrine/paracrine factor to maintain neurogenesis in the central nervous system. It is also a component of the MCDF2-LMAN1 complex that functions as a specific cargo receptor for the ER to Golgi transport of proteins. Mutations in MCFD2 causes factor 5 and factor 8 combined deficiency.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.