SCN11A Antibody (anti-Nav1.9) - Humanized - Low Endotoxin, Azide and BSA Free

• Reactivity: Hu
• Applications: ELISA, Flow, Func
• Clone: anti-Nav1.9
• Clonality: Monoclonal
• Host: Human
• Conjugate: Unconjugated
• Format: Low Endotoxin, Azide and BSA Free
• Concentration: LYOPH

SCN11A Antibody (anti-Nav1.9) - Humanized - Low Endotoxin, Azide and BSA Free Summary

• Description: The heavy chain type is huIgG1, and the light chain type is hukappa. It has a predicted MW of 145.5 kDa.
  
  This product is shipped at ambient temperature. Upon receipt, store immediately at -20C or lower for 12 months in a lyophilized state. - 80C for 3 months after reconstitution. Avoid repeated freeze-thaw cycles.
  
  Patent #: US20200087393
• Additional Information: Recombinant Monoclonal Antibody
• Immunogen: SCN11a / Nav1.9
• Source: CHO
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Human
• Gene: SCN11A
• Purity: Protein A purified
• Endotoxin Note: < 0.001EU/ug,determined by LAL method.

Applications/Dilutions

• Dilutions:
  • ELISA
  • Flow Cytometry
  • Functional

Packaging, Storage & Formulations

• Storage: Store at -20C in powder form. Store at -80C once reconstituted.
• Buffer: Lyophilized from 25mM histidine, 8% sucrose, 0.01% Tween80 (pH6.2)
• Preservative: No Preservative
• Concentration: LYOPH
• Purity: Protein A purified
• Reconstitution Instructions: Reconstitute with sterile, distilled water to a final concentration of 1 mg/ml. Gently shake to solubilize completely. Do not vortex.

Alternate Names for SCN11A Antibody (anti-Nav1.9) - Humanized - Low Endotoxin, Azide and BSA Free

• hNaN
• NaN
• Nav1.9
• Peripheral nerve sodium channel 5
• PN5
• SCN11A
• SCN12A
• SNS2
• SNS-2
• sodium channel, voltage-gated, type XI, alpha polypeptide
• sodium channel, voltage-gated, type XI, alpha subunit
• sodium channel, voltage-gated, type XII, alpha
• voltage-gated sodium channel Nav1.9
• Voltage-gated sodium channel subunit alpha Nav1.9
• voltage-gated, type XII, alpha polypeptide

Background

Voltage-gated sodium channels are membrane protein complexes that play a fundamental role in generating and transmitting action potentials in neuronal cells. SCN11A (Sodium channel, voltage-gated, type XI, alpha subunit) mediates the voltage-dependent sodium ion permeability and conductance. It forms the pore of the sodium-selective channel through which sodium ions may pass in accordance with their electrochemical gradient. It is a tetrodotoxin-resistant sodium channel isoform.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: SCN11A
• Uniprot:
  • Q9UI33(Human)