RNF213 Antibody

Western Blot: RNF213 Antibody [NBP2-76355] - Samples: Whole cell lysate (50 ug) from Jurkat, A-549, and GaMG cells prepared using NETN lysis buffer. Antibody: Affinity purified rabbit anti-RNF213 antibody NBP2-76355 used for WB at 1:1000. Detection: Chemiluminescence with an exposure time of 10 seconds.

Product Discontinued

RNF213 Antibody Summary

• Immunogen: Immunogen sequence is betwen amino acids 4300 and 4350
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: RNF213
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Western Blot 1:1000

Packaging, Storage & Formulations

• Storage: Store at 2 - 8 C / 1 year from date of receipt
• Buffer: Tris-buffered Saline, 0.1% BSA
• Preservative: 0.09% Sodium Azide
• Purity: Antigen Affinity-purified

Alternate Names for RNF213 Antibody

• ALK lymphoma oligomerization partner on chromosome 17
• C17orf27
• chromosome 17 open reading frame 27
• DKFZp762N1115
• FLJ13051
• KIAA1554MGC46622
• KIAA1618
• MGC9929
• NET57
• protein ALO17
• ring finger protein 213

Background

RNF213 is an E3 ubiquitin-protein ligase involved in angiogenesis. Involved in the non-canonical Wnt signaling pathway in vascular development: acts by mediating ubiquitination and degradation of FLNA and NFATC2 downstream of RSPO3, leading to inhibit the non-canonical Wnt signaling pathway and promoting vessel regression. Also has ATPase activity.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: RNF213