Rheb Antibody (344912) [Alexa Fluor® 647]

• Applications: WB, ICC/IF
• Clone: 344912
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: Alexa Fluor 647

Rheb Antibody (344912) [Alexa Fluor® 647] Summary

• Immunogen: E. coli-derived recombinant human Rheb
  Met1-Met184
  Accession # AAH66307
• Specificity: Detects human, mouse, and rat Rheb.
• Isotype: IgG2b
• Clonality: Monoclonal
• Host: Mouse
• Purity Statement: Protein A or G purified

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Background

Ras homolog enriched in brain (Rheb) is a novel member of the Ras superfamily of GTP-binding proteins involved in cell growth and cell cycle progression. Expressed in a wide range of tissues, Rheb was initially identified from its induction in rat hippocampal granule cells by seizures and NMDA-dependent synaptic activity. A complex containing the tuberous sclerosis gene products TSC1 and TSC2 functions as a GTPase-activating protein (GAP) for Rheb.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.