RGS17 Antibody

Western Blot: RGS17 Antibody [NBP1-33694] - Sample (30 ug of whole cell lysate) A: Non-transfected 293T lysates B: RGS17 transfected 293T lysates 12% SDS PAGE; antibody diluted at 1:5000.

Immunocytochemistry/Immunofluorescence: RGS17 Antibody [NBP1-33694] - Paraformaldehyde-fixed A431, using antibody at 1:200 dilution.

Western Blot: RGS17 Antibody [NBP1-33694] - Hep G2 lysates using NBP1-33694 at a dilution of 1:1000. 30ug whole cell lysate loaded on 12% SDS PAGE gel.

• Reactivity: Hu
• Applications: WB, ICC/IF
• Clonality: Polyclonal
• Host: Rabbit
• Conjugate: Unconjugated

RGS17 Antibody Summary

• Immunogen: Carrier-protein conjugated synthetic peptide encompassing a sequence within the C-terminus region of human RGS17. The exact sequence is proprietary.
• Localization: Membrane, Lipid-anchor, Nucleus, Cytoplasm
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: RGS17
• Purity: Antigen Affinity-purified

Applications/Dilutions

• Dilutions:
  • Immunocytochemistry/ Immunofluorescence 1:100-1:1000
  • Western Blot 1:1000-1:10000

Packaging, Storage & Formulations

• Storage: Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
• Buffer: PBS (pH 7), 20% Glycerol, 1% BSA
• Preservative: 0.01% Thimerosal
• Purity: Antigen Affinity-purified

Alternate Names for RGS17 Antibody

• hRGS17
• regulator of G-protein signaling 17
• regulator of G-protein signalling 17
• RGS-17
• RGSZ2

Background

This gene encodes a member of the regulator of G-protein signaling family. This protein contains a conserved, 120 amino acid motif called the RGS domain and a cysteine-rich region. The protein attenuates the signaling activity of G-proteins by binding to activated, GTP-bound G alpha subunits and acting as a GTPase activating protein (GAP), increasing the rate of conversion of the GTP to GDP. This hydrolysis allows the G alpha subunits to bind G beta/gamma subunit heterodimers, forming inactive G-protein heterotrimers, thereby terminating the signal.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause reproductive toxicity with developmental effects.  For more information go to www.P65Warnings.ca.gov.

Bioinformatics

• Gene Symbol: RGS17