Recombinant Human IFN-alpha J1 (alpha 7) Protein

• Reactivity: Hu

Recombinant Human IFN-alpha J1 (alpha 7) Protein Summary

• Protein/Peptide Type: Recombinant Proteins
• Gene: IFNA7

Applications/Dilutions

Publications

Read Publication using 11160-1 in the following applications: Bioassay 1 publication

Packaging, Storage & Formulations

• Storage: Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for Recombinant Human IFN-alpha J1 (alpha 7) Protein

• IFNA7
• IFN-alpha 7
• IFNalpha J1
• IFN-alpha J1
• interferon alpha-7
• interferon alpha-J1
• interferon, alpha 7

Background

Interferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa ligand binding and signal transduction subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. IFN-alpha has both anti-viral and immunomodulatory activities on target cells.

Publications for IFN-alpha J1/IFNA7 (11160-1)(1)

Publication using 11160-1

• Wilson TR, Fridlyand J, Yan Y, Penuel E, Burton L, Chan E, Peng J, Lin E, Wang Y, Sosman J, Ribas A, Li J, Moffat J, Sutherlin DP, Koeppen H, Merchant M, Neve R, Settleman J Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature, 2012-07-26;487(7408):505-9. 2012-07-26 [PMID: 22763448] (Bioassay, Human)

Bioinformatics

• Gene Symbol: IFNA7