RASA3 Antibody

Product Discontinued

RASA3 Antibody Summary

• Immunogen: Peptide with sequence C-QYKRDKFKKTKYGSQ corresponding to internal region (near C-Terminus) according to NP_031394.2.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: RASA3
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Peptide ELISA Detection limit 1:32000
• Application Notes: WB: Preliminary experiments in human brain lysates gave no specific signal but low background.-

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris saline (20 mM Tris pH 7.3, 150 mM NaCl), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for RASA3 Antibody

• GAP1(IP4BP)
• GAP1IP4BP
• GAPIII
• GTPase activating protein III
• inositol 13,4,5-tetrakisphosphate-binding protein
• Ins P4-binding protein
• Ins(13,4,5)P4-binding protein
• MGC46517
• MGC47588
• ras GTPase-activating protein 3
• RAS p21 protein activator 3

Background

RASA3 is a inhibitory regulator of the Ras-cyclic AMP pathway. It binds inositol tetrakisphosphate (IP4) with high affinity. RASA3 might be a specific IP4 receptor.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for RASA3 Antibody (NB100-1495)(1)

Publication using NB100-1495

• Kuai J, Wooters J, Hall JP et al. NAK is recruited to the TNFR1 complex in a TNFalpha-dependent manner and mediates the production of RANTES: identification of endogenous TNFR-interacting proteins by a proteomic approach. J Biol Chem 2004-12-17 [PMID: 15485837]

Bioinformatics

• Gene Symbol: RASA3
• Entrez:
  • 22821(Human)
  • 19414(Mouse)
  • 29372(Rat)
• Uniprot:
  • NP_031394.(Human)