RAMP2 Antibody

Images

 
Western blot shows lysates of D3 mouse embryonic stem cell line. PVDF Membrane was probed with 1 µg/mL of Mouse RAMP2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6500) followed by HRP-conjugated ...read more
bEnd.3 mouse endothelioma cell line was stained with Mouse RAMP2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF6500, filled histogram) or control antibody (Catalog # 5-001-A, open histogram), followed by ...read more

Product Details

Summary
Reactivity MuSpecies Glossary
Applications WB, Flow, CyTOF-ready
Clonality
Polyclonal
Host
Sheep
Conjugate
Unconjugated
Concentration
LYOPH

Order Details

View Available Formulations
Catalog# & Formulation Size Price

RAMP2 Antibody Summary

Immunogen
E. coli-derived recombinant mouse RAMP2
Ser45-Val159
Accession # Q9WUP0
Specificity
Detects mouse RAMP2 in direct ELISAs and Western blots. In direct ELISAs, approximately 25% cross-reactivity with recombinant human (rh) RAMP2 is observed, and less than 1% cross-reactivity with rhRAMP1 is observed.
Source
N/A
Isotype
IgG
Clonality
Polyclonal
Host
Sheep
Gene
RAMP2
Purity
Immunogen affinity purified
Purity Statement
Antigen Affinity-purified
Innovator's Reward
Test in a species/application not listed above to receive a full credit towards a future purchase.

Applications/Dilutions

Dilutions
  • Western Blot 1 ug/mL
  • Flow Cytometry 2.5 ug/10^6 cells
  • CyTOF-ready

Packaging, Storage & Formulations

Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Buffer
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Preservative
No Preservative
Concentration
LYOPH
Purity
Immunogen affinity purified
Reconstitution Instructions
Sterile PBS to a final concentration of 0.2 mg/mL.

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for RAMP2 Antibody

  • calcitonin receptor-like receptor activity modifying protein 2
  • Calcitonin-receptor-like receptor activity-modifying protein 2
  • CRLR activity-modifying protein 2
  • RAMP2
  • receptor (calcitonin) activity modifying protein 2
  • receptor (G protein-coupled) activity modifying protein 2
  • receptor activity modifying protein 2
  • receptor activity-modifying protein 2
  • receptor-activity-modifying protein 2

Background

RAMP2 (receptor activity modifying protein 2) is a 20 kDa member of the RAMP family of proteins. It is expressed on cardiomyocytes, vascular smooth muscle cells and endothelium, and interacts with CRLR to form a receptor complex for adrenomedullin (AM). AM induces vasodilation on AM1 receptor expressing cells. Mature mouse RAMP2 is a 145 amino acid (aa) type I transmembrane glycoprotein that contains a 115 aa extracellular domain (ECD) (aa 45-159) and a nine aa cytoplasmic region. Although the ECD contains no typical structural motifs, based on human, aa 100-106 are critical for AM binding. Over aa 45-159, mouse RAMP2 shares 57% and 83% aa identity with human and rat RAMP2, respectively.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Customers Who Viewed This Item Also Viewed...

NLS6731
Species: Hu, Rt, Po, Bv, Ca, Eq, Gt, Ha, Pm, Pm, Rb, Xp
Applications: IHC, IHC-P
AF4875
Species: Hu
Applications: WB
NBP2-94078
Species: Hu, Mu, Rt
Applications: WB, ICC/IF
NBP2-78736
Species: Hu
NB120-14817
Species: Hu, Rt
Applications: WB, ICC/IF, IHC, S-ELISA
AF1052
Species: Hu
Applications: WB, Flow, IHC, CyTOF-ready
NB100-40840
Species: Hu, Mu
Applications: WB, IHC, IHC-P, IP
NB100-56490
Species: Hu, Ca, Pm
Applications: WB, IHC, IHC-P
AF6517
Species: Hu
Applications: WB
NLS4048
Species: Hu, Pm
Applications: WB, IHC, IHC-P, ICC
MAB4614
Species: Hu
Applications: Flow, CyTOF-ready, KO
21890002
Species: Hu
Applications: WB, ELISA, IHC, IHC-P
NBP1-06579
Species: Hu, Mu, Rt
Applications: WB, ELISA, IHC, IHC-P
NLS418
Species: Hu
Applications: IHC, IHC-P
NLS2756
Species: Hu, Pm
Applications: IHC, IHC-P, ICC
NLS442
Species: Hu, Mu
Applications: IHC, IHC-Fr, IHC-P
NLS2272
Species: Hu, Pm, Pm
Applications: IHC, IHC-P

Publications for RAMP2 Antibody (AF6500) (0)

There are no publications for RAMP2 Antibody (AF6500).
By submitting your publication information earn gift cards and discounts for future purchases.

Reviews for RAMP2 Antibody (AF6500) (0)

There are no reviews for RAMP2 Antibody (AF6500). By submitting a review you will receive an Amazon e-Gift Card or Novus Product Discount.
  • Review with no image -- $10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen
  • Review with an image -- $25/€18/£15/$25 CAD/¥150 Yuan/¥2500 Yen

Product General Protocols

Find general support by application which include: protocols, troubleshooting, illustrated assays, videos and webinars.

Video Protocols

WB Video Protocol

FAQs for RAMP2 Antibody (AF6500) (0)

There are no specific FAQs related to this product. Read our general customer & technical service FAQs.

Secondary Antibodies

 

Isotype Controls

Other Available Formats

Additional RAMP2 Products

Bioinformatics Tool for RAMP2 Antibody (AF6500)

Discover related pathways, diseases and genes to RAMP2 Antibody (AF6500). Need help? Read the Bioinformatics Tool Guide for instructions on using this tool.
Visit Tool

Diseases for RAMP2 Antibody (AF6500)

Discover more about diseases related to RAMP2 Antibody (AF6500).
 

Pathways for RAMP2 Antibody (AF6500)

View related products by pathway.

PTMs for RAMP2 Antibody (AF6500)

Learn more about PTMs related to RAMP2 Antibody (AF6500).

Blogs on RAMP2

There are no specific blogs for RAMP2, but you can read our latest blog posts.
Coronavirus Brochure

Customers Who Bought This Also Bought

Contact Information

Learn the difference between western blot and simple western

Product PDFs

Calculators

Concentration Calculator

The concentration calculator allows you to quickly calculate the volume, mass or concentration of your vial. Simply enter your mass, volume, or concentration values for your reagent and the calculator will determine the rest.

=
÷

Review this Product

Be the first to review our RAMP2 Antibody and receive a gift card or discount.

Bioinformatics

Gene Symbol RAMP2
Uniprot