Species: Hu, Pm
Applications: WB, Flow, IHC
Host: Mouse Monoclonal
Species: Mu
Applications: Flow, IHC, CyTOF-ready
Host: Rat Monoclonal
Species: Mu
Applications: WB, Flow, CyTOF-ready
Host: Sheep Polyclonal
Species: Hu
Applications: ELISA
Species: Hu
Applications: ELISA
Species: Hu
Applications: WB
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: WB, ELISA, MA, AP
Species: Hu
Applications: AC
Description
The protein encoded by the RAMP2 gene is a member of the RAMP family of single-transmembrane-domain proteins, called receptor (calcitonin) activity modifying proteins (RAMPs). RAMPs are type I transmembrane proteins with an extracellular N terminus and a cytoplasmic C terminus. RAMPs are required to transport calcitonin-receptor-like receptor (CRLR) to the plasma membrane. CRLR, a receptor with seven transmembrane domains, can function as either a calcitonin-gene-related peptide (CGRP) receptor or an adrenomedullin receptor, depending on which members of the RAMP family are expressed. In the presence of this (RAMP2) protein, CRLR functions as an adrenomedullin receptor. The RAMP2 protein is involved in core glycosylation and transportation of adrenomedullin receptor to the cell surface.
Bioinformatics
| Entrez |
Human
|
| Uniprot |
Human
Human
|
| Product By Gene ID |
10266 |
| Alternate Names |
- calcitonin receptor-like receptor activity modifying protein 2
- Calcitonin-receptor-like receptor activity-modifying protein 2
- CRLR activity-modifying protein 2
- receptor (calcitonin) activity modifying protein 2
- receptor (G protein-coupled) activity modifying protein 2
- receptor activity modifying protein 2
- receptor activity-modifying protein 2
- receptor-activity-modifying protein 2
|
![Flow Cytometry RAMP2 Antibody (773816) [Unconjugated]](http://images.novusbio.com/fullsize2/12869.jpg)
![Immunohistochemistry RAMP2 Antibody (773816) [Unconjugated]](http://images.novusbio.com/fullsize2/RAMP2_MAB6500_Immunohistochemistry_12918.jpg)
