RalB Antibody (399417) [Alexa Fluor® 647]

• Reactivity: Hu
• Applications: WB
• Clone: 399417
• Clonality: Monoclonal
• Host: Rat
• Conjugate: Alexa Fluor 647

RalB Antibody (399417) [Alexa Fluor® 647] Summary

• Immunogen: E. coli-derived recombinant human RalB
  Met1-Leu206
  Accession # P11234
• Specificity: Detects human, mouse, and rat RalB in Western blots. In Western blots, no cross-reactivity with recombinant human RalA is observed.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Rat
• Purity Statement: Protein A or G purified

Applications/Dilutions

• Dilutions:
  • Western Blot

Packaging, Storage & Formulations

• Storage: Protect from light. Do not freeze. 12 months from date of receipt, 2 to 8 °C as supplied
• Buffer: Supplied 0.2mg/ml in 1X PBS with RDF1 and 0.09% Sodium Azide

Notes

This product is produced by and ships from R&D Systems, Inc., a Bio-Techne brand.

Alternate Names for RalB Antibody (399417) [Alexa Fluor® 647]

• GTP binding protein
• RalB
• RAS-like protein B
• ras-related protein Ral-B
• v-ral simian leukemia viral oncogene homolog B (ras related; GTP bindingprotein)

Background

The Ras-like proteins RalA and RalB share 85% identity and constitute a grouping within the Ras superfamily of small GTPases. Like other GTPases, Ral proteins transduce signals by cycling between an active GTP-bound and an inactive GDP-bound state. Ral functions as an effector of Ras-mediated signaling, and has been implicated in the regulation of vesicle trafficking and cell morphology.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.