Recombinant Human Rab24 Protein

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Product Details

Summary
Reactivity HuSpecies Glossary
Applications PAGE
Concentration
0.5 mg/ml

Order Details

Recombinant Human Rab24 Protein Summary

Description
A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-203 of Human Rab24

Source: E.coli

Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MGSHMSGQRV DVKVVMLGKE YVGKTSLVER YVHDRFLVGP YQNTIGAAFV AKVMSVGDRT VTLGIWDTAG SERYEAMSRI YYRGAKAAIV CYDLTDSSSF ERAKFWVKEL RSLEEGCQIY LCGTKSDLLE EDRRRRRVDF HDVQDYADNI KAQLFETSSK TGQSVDELFQ KVAEDYVSVA AFQVMTEDKG VDLGQKPNPY FYSCCHH

Source
E. coli
Protein/Peptide Type
Recombinant Protein
Gene
RAB24
Purity
>90%, by SDS-PAGE

Applications/Dilutions

Theoretical MW
25.7 kDa.
Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

Storage
Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
Buffer
20mM Tris-HCl buffer (pH 8.0) containing 2mM DTT, 30% glycerol, 100mM NaCl, 1mM EDTA
Preservative
No Preservative
Concentration
0.5 mg/ml
Purity
>90%, by SDS-PAGE

Alternate Names for Recombinant Human Rab24 Protein

  • RAB24, member RAS oncogene family
  • ras-related protein Rab-24

Background

RAB24 belongs to the small GTPase superfamily. Members of the Rab GTPase family regulate intracellular protein trafficking, but the specific function of RAB24 remains unknown. RAB24 is distributed in the endoplasmic reticulum/cis-Golgi region and on late endosomal structures, and this subcellular distribution pattern of RAB24 may indicate its involvement in autophagy-related processes. RAB24 presents unusual characteristics, including low intrinsic GTPase activity, and is inefficiently prenylated when compared with other Rab proteins. Also suggested that RAB24 might play a unique role in the degradation of misfolded cellular proteins or trafficking of proteins to the nuclear envelope. Recombinant human RAB24 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

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Bioinformatics

Gene Symbol RAB24