RAB15 Recombinant Protein Antigen

Product Discontinued

RAB15 Recombinant Protein Antigen Summary

• Description: A recombinant protein antigen with a N-terminal His6-ABP tag corresponding to human RAB15.
  
  

  Source: E. coli

  Amino Acid Sequence: QPWMKTSGTHQKASRRSLLGIRLMRSRNGRWEESKGSSWRRSMAWTSMKQVPAPTSTLKSHS

  Fusion Tag: N-terminal His6ABP (ABP = Albumin Binding Protein derived from Streptococcal Protein G)

  This product is intended to be used as a blocking antigen for antibody competition assays. Any other use of this antigen is done at the risk of the user. The use of this product for commercial production is strictly prohibited. Please contact technical support if you have any questions.

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein Antigen
• Gene: RAB15
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Applications/Dilutions

• Dilutions:
  • Antibody Competition 10 - 100 molar excess
• Application Notes: This recombinant antigen is only intended to be used as a blocking agent to confirm antibody specificity with the corresponding antibody, catalog number NBP1-86231.

  It is purified by IMAC chromatography, and the expected concentration is greater than 0.5 mg/ml.

  For current lot information, including availability, please contact our technical support team click nb-technical@bio-techne.com

• Theoretical MW: 25 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: PBS and 1M Urea, pH 7.4.
• Preservative: No Preservative
• Purity: >80% by SDS-PAGE and Coomassie blue staining

Alternate Names for RAB15 Recombinant Protein Antigen

• RAB15, member RAS oncogene family
• RAB15, member RAS onocogene family
• ras-related protein Rab-15

Background

RAB15, also known as Ras-related protein Rab-15, is a 24 kDa 212 amino acid protein with a shorter, 24 kDa 208 isoform. The gene functions as a regulator of synaptic vesicle membrane flow and may act in unity with RAB3A. Current research is being conducted on RAB15 in relation to differentiating neuroblastoma, pulmonary disease and neuroblastoma. RAB15 is linked to the exocytosis, secretion, endocytosis, cell differentiation, angiogenesis and localization pathways where it interacts with RABIF, RPH3A, ATG5, CLN3 and GABARAPL1.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Bioinformatics

• Gene Symbol: RAB15