PYK2/FAK2 [p Tyr402] Antibody (592918) [mFluor Violet 450 SE]

• Reactivity: Hu
• Applications: WB
• Clone: 592918
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: mFluor Violet 450 SE

PYK2/FAK2 [p Tyr402] Antibody (592918) [mFluor Violet 450 SE] Summary

• Immunogen: Phosphopeptide containing the human PYK2/FAK2 Y402 site
  Accession # Q14289
• Modification: p Tyr402
• Specificity: Detects human PYK2/FAK2 when phosphorylated at Y402.
• Isotype: IgG1
• Clonality: Monoclonal
• Host: Mouse
• Gene: PTK2B
• Purity: Protein A or G purified from hybridoma culture supernatant

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Protein A or G purified from hybridoma culture supernatant

Notes

mFluor(TM) is a trademark of AAT Bioquest, Inc. This conjugate is made on demand. Actual recovery may vary from the stated volume of this product. The volume will be greater than or equal to the unit size stated on the datasheet.

Alternate Names for PYK2/FAK2 [p Tyr402] Antibody (592918) [mFluor Violet 450 SE]

• CADTK
• CADTKCAK-beta
• CAK beta
• CAKB
• Calcium-dependent tyrosine kinase
• Cell adhesion kinase beta
• EC 2.7.10
• FADK2
• FAK2
• FAK2EC 2.7.10.2
• Focal adhesion kinase 2
• FRNK
• PKB
• ppyk2
• Proline-rich tyrosine kinase 2
• protein kinase B
• protein tyrosine kinase 2 beta
• protein-tyrosine kinase 2-beta
• PTK
• PTK2B protein tyrosine kinase 2 beta
• PTK2B
• PYK2
• PYK2Related adhesion focal tyrosine kinase
• RAFTK
• RAFTKFADK 2

Background

Proline rich protein tyrosine kinase (Pyk2) is a focal adhesion kinase (FAK2) related protein kinase protein also known as cell adhesion kinase (CAK ), related adhesion focal tyrosine kinase (RAFTK), or calcium-dependent PTK (CADTK) (3.4). Highly expre ed in the nervous system, protein tyrosine kinase (Pyk2) is phosphorylated on the tyrosine residue by a variety of G-protein-coupled receptors & extracellular signals that increase the level of Ca+ intracellulary (1,2)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PTK2B