PTGFR Antibody

Immunohistochemistry-Paraffin: PTGFR Antibody [NLS6624] - Anti-FP / PTGFR antibody IHC of human Ovary, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Immunohistochemistry-Paraffin: PTGFR Antibody [NLS6624] - Analysis of anti-PTGFR antibody with human ovary.

Immunohistochemistry-Paraffin: PTGFR Antibody [NLS6624] - Analysis of anti-PTGFR antibody with uterus at dilution 20 ug/ml.

Immunohistochemistry-Paraffin: PTGFR Antibody [NLS6624] - Analysis of anti-PTGFR antibody with human brain, glioblastoma.

Immunohistochemistry-Paraffin: PTGFR Antibody [NLS6624] - Human Skin, Melanoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

Product Discontinued

PTGFR Antibody Summary

• Immunogen: Synthetic 18 amino acid peptide from 1st extracellular domain of human PTGFR.
• Specificity: Human PTGFR. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
• Predicted Species: Equine (94%), Monkey (94%). Backed by our 100% Guarantee.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Rabbit
• Gene: PTGFR
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Paraffin 4 - 20 ug/ml

Reactivity Notes

Predicted cross-reactivity based on sequence identity: Gibbon (94%), Marmoset (89%), Mosue (89%), Rat (89%), Elephant (89%), Panda (89%), Bat (89%), Canine (89%), Rabbit (89%), Porcine (89%), Turkey (83%), Chicken (83%), Platypus (83%).

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: PBS
• Preservative: 0.1% Sodium Azide
• Concentration: 1.0 mg/ml
• Purity: Immunogen affinity purified

Alternate Names for PTGFR Antibody

• FP
• MGC120498
• MGC46203
• PGF receptor
• PGF2 alpha receptor
• PGF2-alpha Receptor
• prostaglandin F receptor (FP)
• prostaglandin F2 alpha receptor
• prostaglandin F2-alpha receptor
• prostaglandin receptor (2-alpha)
• Prostanoid FP receptor
• PTGFR

Background

The prostaglandin F2-alpha receptor is a member of the Prostanoid Receptor subfamily. Along with various other prostaglandin receptors, it mediates the effects of prostaglandin F(2-alpha) which include modulation of intraocular pressure, corpus luteum regression, and possibly uterine smooth muscle contraction. Alternative mRNA splicing gives rise to two isoforms, FP(A) and FP(B), that differ in their intracellular carboxyl termini and result in different mechanisms for receptor internalization. Prostaglandin F2-alpha receptor expression has been documented in eye, ovary, placenta, and uterus. ESTs have been isolated from placental libraries.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: PTGFR
• Entrez:
  • 5737(Human)
• Uniprot:
  • P43088()