PSPHL Antibody

Product Discontinued

PSPHL Antibody Summary

• Immunogen: Peptide with sequence HWIWRKCDQATSQG corresponding to C-Terminus according to NP_003823.1.
• Isotype: IgG
• Clonality: Polyclonal
• Host: Goat
• Gene: PSPHP1
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Immunohistochemistry
  • Immunohistochemistry-Frozen
  • Peptide ELISA Detection limit 1:16000
• Application Notes: WB: Not yet tested - Our standard WB protocol would not expect to reliably detect proteins as small as the predicted MW of approx. 7.80 kDa band according to NP_003823. Use in Immunohistochemistry-Frozen reported in scientific literature (PMID: 17652725).

Packaging, Storage & Formulations

• Storage: Store at -20C. Avoid freeze-thaw cycles.
• Buffer: Tris (pH 7.3), 0.5% BSA
• Preservative: 0.02% Sodium Azide
• Concentration: 0.5 mg/ml
• Purity: Immunogen affinity purified

Notes

Please note, this antibody is considered Innovators Grade. Innovators Grade antibodies are generally unvalidated and require additional characterization for most new species/applications. Novus has made these antibodies available through our Innovators Reward program. Complete an online review with image, detailing your positive or negative results. In return, you receive a discount voucher for 100% of the purchase price of the reviewed product. Please contact us at innovators@novusbio.com for more details.

Alternate Names for PSPHL Antibody

• CO9
• phosphoserine phosphatase pseudogene 1
• PSPHL

Background

The PSPHL gene is significantly upregulated in Fanconi's anemia fibroblasts but downregulated or absent in fibroblasts from normal donors. It is also highly expressed in FA B-cells of complementation group A. (provided by RefSeq)

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Publications for PSPHL Antibody (NB300-964)(2)

Publications using NB300-964

• Kuo CH, Miyazaki D, Nawata N et al. Prognosis-determinant candidate genes identified by whole genome scanning in eyes with pterygia. Invest Ophthalmol Vis Sci. 2007-08-01 [PMID: 17652725] (IHC-Fr, Human)
  
  Details:
  IHC (frozen): human soft conjunctival tissues, Fig. 3e,f.
• Planitzer SA, Machl AW, Rueckels M, Kubbies M. Identification of a novel c-DNA overexpressed in Fanconi's anemia fibroblasts partially homologous to a putative L-3-phosphoserine-phosphatase. Gene 1998-04-14 [PMID: 9573387]

Bioinformatics

• Gene Symbol: PSPHP1
• Entrez:
  • 8781(Human)