Recombinant Human Prostaglandin E Synthase 2/PTGES2 Protein

Product Discontinued

Recombinant Human Prostaglandin E Synthase 2/PTGES2 Protein Summary

• Description: A recombinant protein with a N-Terminal His-tag and corresponding to the amino acids 1-186 of Human Prostaglandin E Synthase 2/PTGES2
  
  

  Source: E.coli

  Amino Acid Sequence: MGSSHHHHHH SSGLVPRGSH MKAVNEQGKE VTEFGNKYWL MLNEKEAQQV YGGKEARTEE MKWRQWADDW LVHLISPNVY RTPTEALASF DYIVREGKFG AVEGAVAKYM GAAAMYLISK RLKSRHRLQD NVREDLYEAA DKWVAAVGKD RPFMGGQKPN LADLAVYGVL RVMEGLDAFD DLMQHTHIQP WYLRVERAIT EASPAH

• Source: E. coli
• Protein/Peptide Type: Recombinant Protein
• Gene: PTGES2
• Purity: >95% pure by SDS-PAGE

Applications/Dilutions

• Dilutions:
  • SDS-Page
• Theoretical MW: 23.5 kDa.
  Disclaimer note: The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.

Packaging, Storage & Formulations

• Storage: Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.
• Buffer: 20 mM Tris-HCl buffer (pH 8.0), 20% glycerol, 2 mM DTT, 0.2 M NaCl, 0.1 mM PMSF
• Preservative: No Preservative
• Concentration: 0.5 mg/ml
• Purity: >95% pure by SDS-PAGE

Alternate Names for Recombinant Human Prostaglandin E Synthase 2/PTGES2 Protein

• C9orf15
• chromosome 9 open reading frame 15
• EC 5.3.99.3
• FLJ14038
• gamma-interferon-activated transcriptional element-binding factor 1
• GATE-binding factor 1
• GBF1
• membrane-associated prostaglandin E synthase 2
• Microsomal prostaglandin E synthase 2
• microsomal prostaglandin E synthase-2
• mPGES2
• mPGES-2
• PGES2
• PGES2MGC11289
• prostaglandin E synthase 2
• PTGES2

Background

PTGES2 is a membrane-associated prostaglandin E synthase, which catalyzes the conversion of prostaglandin H2 to prostaglandin E2. This protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element. Recombinant human PTGES2 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Peptides and proteins are guaranteed for 3 months from date of receipt.

Publications for Prostaglandin E Synthase 2/PTGES2 Recombinant Protein (NBP1-72306)(1)

Publication using NBP1-72306

• Yang L, Tong Y, Chen PF et al. Neuroprotection of dihydrotestosterone via suppression of the toll-like receptor 4/nuclear factor-kappa B signaling pathway in high glucose-induced BV-2 microglia inflammatory responses Neuroreport 2020-01-27 [PMID: 31876682]

Bioinformatics

• Gene Symbol: PTGES2