PRAK Antibody (OTI5E1) [DyLight 650]

• Reactivity: Hu, Mu, Rt
• Applications: WB
• Clone: OTI5E1
• Clonality: Monoclonal
• Host: Mouse
• Conjugate: DyLight 650

PRAK Antibody (OTI5E1) [DyLight 650] Summary

• Immunogen: Recombinant protein fragment corresponding to amino acids 197-471 of human PRAK (NP_003659) produced in E.coli.
• Isotype: IgG2a
• Clonality: Monoclonal
• Host: Mouse
• Gene: MAPKAPK5
• Purity: Immunogen affinity purified

Applications/Dilutions

• Dilutions:
  • Western Blot
• Application Notes: Optimal dilution of this antibody should be experimentally determined.

Packaging, Storage & Formulations

• Storage: Store at 4C in the dark.
• Buffer: 50mM Sodium Borate
• Preservative: 0.05% Sodium Azide
• Purity: Immunogen affinity purified

Notes

DyLight (R) is a trademark of Thermo Fisher Scientific Inc. and its subsidiaries.

Alternate Names for PRAK Antibody (OTI5E1) [DyLight 650]

• EC 2.7.11
• MAP kinase-activated protein kinase 5
• MAPK-activated protein kinase 5
• MAPKAP kinase 5
• MAPKAPK-5
• mitogen-activated protein kinase-activated protein kinase 5
• p38-regulated/activated protein kinase
• PRAKEC 2.7.11.1

Background

PRAK is encoded by this gene is a member of the serine/threonine kinase family. In response to cellular stress and proinflammatory cytokines, this kinase is activated through its phosphorylation by MAP kinases including MAPK1/ERK, MAPK14/p38-alpha, and MAPK11/p38-beta. In vitro, this kinase phosphorylates heat shock protein HSP27 at its physiologically relevant sites. Two alternately spliced transcript variants of this gene encoding distinct isoforms have been reported.

Limitations

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

Bioinformatics

• Gene Symbol: MAPKAPK5